PUBLICATIONS

JEAN YIN JEN WANG

 

 

1. Suelter, C.H., J.Y.J. Wang and E.E. Snell. (1976).  Application of a direct spectrophotometric assay employing a chromogenic substrate for tryptophanase to the determination of pyridoxal and pyridoxamine 5'-phosphate.  Anal. Biochem. 76:221-232.

 

2. Suelter, C.H., J.Y.J. Wang and E.E. Snell. (1976).  Direct spectrophotometric assay of tryptophanase.  FEBS Lett. 66:230-232.

 

3. Wang, J.Y.J. and D.E. Koshland Jr. (1978).  Evidence for protein kinase activities in the procaryote Salmonella typhimurium.  J. Biol. Chem. 253:7605-7608.

 

4. Wang, J.Y.J., D.O. Clegg and J. Koshland D E. (1981).  Molecular cloning and amplification of the bacterial adenylate cyclase gene.  Proc. Natl. Acad. Sci. USA 78:4684-4688.

 

5. Wang, J.Y.J. and J. Koshland D E. (1981).  The identification of distinct protein kinases and phosphates in the procaryote Salmonella typhimurium.  J. Biol. Chem. 256:4640-4648.

 

6. Wang, J.Y.J. and J. Koshland D E. (1981). Protein phosphorylation in procaryotes.  In: Cold Spring Harbor Conference on Cell Proliferation, Vol. 8.  eds. Protein Phosphorylation, pp. 637-643.

 

7. Goff, S.P., C. Tabin, J.Y.J. Wang, R. Weinberg and D. Baltimore. (1982).  Transfection of fibroblasts with clone Abelson Murine Leukemia Virus DNA and recovery of transmissible virus by recombination with helper virus.  J. Virol. 41:271-285.

 

8. Wang, J.Y.J. and D.E. Koshland Jr. (1982).  The reversible phosphorylation of isocitrate dehydrogenase in Salmonella typhimurium.  Arch. Biochem. Biophys. 218:59-67.

 

9. Wang, J.Y.J., C. Queen and D. Baltimore. (1982).  Expression of an Abelson Murine Leukemia Virus-encoded protein in Escherichia coli causes extensive phosphorylation of tyrosine residues.  J. Biol. Chem. 257:13181-13184.

 

10. Latt, S.A., S.P. Goff, C. Tabin, M. Paskind, J.Y.J. Wang and D. Baltimore. (1983).  Cloning and analysis of reverse transcript P160 genomes of Abelson Murine Leukemia Virus.  J. Virol. 45:1195-1199.

 

11. Wang, J.Y.J. (1983).  From c-abl to v-abl.  Nature 304:400.

 

12. Wang, J.Y.J. and D. Baltimore. (1983).  Characterization of the Abelson Murine Leukemia Virus-encoded tyrosine specific protein kinase.  Meth. Enzymol. 99:373-378.

 

13. Wang, J.Y.J. and D. Baltimore. (1983).  Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.  Mol. Cell. Biol. 3:773-779.

 

14. Wang, J.Y.J., R. Prywes and D. Baltimore. (1983a). Structure and function of the Abelson Murine Leukemia Virus transforming gene.  In: Oncogenes and Retroviruses, Evaluation of Basic Findings and Clinical Potential.  O'Connor, T.E. and F.J. Rauscher Jr., eds. Alan R. Liss, Inc., pp. 57-66.

 

15. Wang, J.Y.J., R. Prywes and D. Baltimore. (1983b). Structure and function of the Abelson Murine Leukemia Virus transforming gene.  In: Leukemia Research: Advances in Cell Biology and Treatment, Vol.  Murphy, S.B. and J.R. Gilbert, eds. Elsevier Biomedical, pp. 9-16.

 

16. Baltimore, D., J.Y.J. Wang and R. Prywes. (1984). The transforming region of the Abelson Murine Leukemia Virus protein is a tyrosine-specific protein kinase.  In: Medicine, Science and Society.  Isselbacher, K.J., ed. Wiley & Sons, pp. 331-336.

 

17. Wang, J.Y.J., F. Ledley, S. Goff, R. Lee, Y. Groner and D. Baltimore. (1984).  The mouse c-abl locus: molecular cloning and characterization.  Cell 36:349-356.

 

18. Wang, J.Y.J. and L.T. Williams. (1984).  Oncogene v-sis-encoded protein competes for PDGF receptors.  J. Biol. Chem. 259:349-356.

 

19. Lee, R., M. Paskind, J.Y.J. Wang and D. Baltimore. (1985). Abelson (p160) murine leukemia virus abl gene.  In: RNA Tumor Viruses.  Weiss, R., N. Teich, H. Varmus and J. Coffin, eds. Cold Spring Harbor Lab., Cold Spring Harbor. pp. 861-868.

 

20. Wang, J.Y.J. (1985).  Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein.  Mol. Cell. Biol. 5:3640-3643.

 

21. Maher, P., E.B. Pasquale, J.Y.J. Wang and S.J. Singer. (1985).  Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells.  Proc. Natl. Acad. Sci. USA 82:6576-6580.

 

22. Wang, J.Y.J. and D. Baltimore. (1985).  Localization of tyrosine kinase coding region in v-abl oncogene by the expression of v-abl-encoded proteins in bacteria.  J. Biol. Chem. 260:64-71.

 

23. Williams, L.T., P.M. Tremble, T.O. Daniel, S.R. Coughlin, G. Giels and J.Y.J. Wang. (1985). Platelet-derived growth factor receptors in normal and transformed cells.  In: Cancer Cells, Growth Factors and Transformation.  Feramisco, J., B. Ozanne and C. Stiles, eds. Cold Spring Harbor Lab., Cold Spring Harbor. pp. 175-182.

 

24. Morla, A.O. and J.Y.J. Wang. (1986).  Protein tyrosine phosphorylation in the cell cycle of Balb/3T3 fibroblasts.  Proc. Natl. Acad. Sci. USA 83:8191-8195.

 

25. Bergold, P.J., J.Y.J. Wang, V. Littau, E. Johnson, W.D. Hardy and P. Besmer. (1987).  Structure and origin of the HZ2-feline sarcoma virus (HZ2-FeSV).  J. Virol. 158:320-329.

 

26. Kipreos, E.T., G.J. Lee and J.Y.J. Wang. (1987).  Isolation of temperature sensitive tyrosine kinase mutants of v-abl oncogene by screening with antibodies for phosphotyrosine.  Proc. Natl. Acad. Sci. USA 84:1345-1349.

 

27. Richardson, J.M., A.O. Morla and J.Y.J. Wang. (1987).  Reduction in protein tyrosine phosphorylation during differentiation of human leukemia cell line K562.  Cancer Res. 47:4066-4070.

 

28. Yonemoto, W., A.J. Filson, A.E. Queral-Lustig, J.Y.J. Wang and J.S. Brugge. (1987).  Detection of phosphotyrosine containing proteins in polyomavirus middle tumor antigen-transformed cells following treatment with a phosphotyrosine phosphatase inhibitor.  Mol. Cell. Biol. 7:905-913.

 

29. Kipreos, E.T. and J.Y.J. Wang. (1988).  Reversible dependence on growth factor interleukin-3 in myeloid cells expressing temperature sensitive v-abl oncogene.  Oncogene Res. 2:277-284.

 

30. Morla, A.O., J. Schreurs, A. Miyajima and J.Y.J. Wang. (1988).  Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3 dependent murine cell lines.  Mol. Cell. Biol. 8:2214-2218.

 

31. Renshaw, M.W., M.A. Capozza and J.Y.J. Wang. (1988).  Differential expression of type-specific c-abl mRNAs in mouse tissues and cell lines.  Mol. Cell. Biol. 8:4547-4551.

 

32. Wang, J.Y.J. (1988).  Negative regulation of c-abl tyrosine kinase by its variable N-terminal amino acids.  Oncogene Res. 3:293-298.

 

33. Wang, J.Y.J. (1988).  Antibodies for phosphotyrosine: Analytical and preparative tool for tyrosyl-phosphorylated proteins.  Anal. Biochem. 172:1-7.

 

34. Chan, P.-L., P. Scully, J.-Y. Shew, J.Y.J. Wang and W.-H. Lee. (1989).  Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation.  Cell 58:1193-1198.

 

35. Cleveland, J.L., M. Dean, N. Rosenberg, J.Y.J. Wang and U.R. Rapp. (1989).  Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeolid cells through signalling pathways involving c-myc: conditional regulation of c-myc transcription by temperature sensitive v-abl.  Mol. Cell. Biol. 9:5685-5695.

 

36. Franz, W.M., P. Berger and J.Y.J. Wang. (1989).  Deletion of an N-terminal regulatory domain of the c-abl tyrosine kinase activates its oncogenic potential.  EMBO J. 8:137-147.

 

37. Morla, A.O., G. Draetta, D. Beach and J.Y.J. Wang. (1989).  Reversible tyrosine phosphorylation of cdc2; dephosphorylation accompanies activation during entry into mitosis.  Cell 58:193-203.

 

38. Kipreos, E.T. and J.Y.J. Wang. (1990).  Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity.  Science 248:217-220.

 

39. Guo, J.Q., J.Y.J. Wang and R.B. Arlinghaus. (1991).  Detection of BCR-ABL proteins in blood cells of benign phase chronic myelogenous leukemia patients.  Cancer Res. 51:3048-3051.

 

40. Lin, B.T.Y., S. Gruenwald, W.-H. Lee and J.Y.J. Wang. (1991).  Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.  EMBO J. 10:857-864.

 

41. McWhirter, J.R. and J.Y.J. Wang. (1991).  Activation of tyrosine kinase and microfilament-binding functions of C-Abl by BCR sequences in BCR/ABL fusion proteins.  Mol. Cell. Biol. 11:1553-1565.

 

42. Meijer, M., L. Azzi and J.Y.J. Wang. (1991).  Cyclin B targets p34cdc2 for tyrosine phosphorylation.  EMBO J. 10:1545-1554.

 

43. Wang, J.Y.J. (1991).  Preparation and use of anti-phosphotyrosine antibodies raised against v-abl oncogene protein.  Methods Enzymol. 201, part II:53-65.

 

44. Welch, P.J. and J.Y.J. Wang. (1992).  Coordinated synthesis and degradation of cdc2 in the mammalian cell cycle.  Proc. Natl. Acad. Sci. USA 89:3093-3097.

 

45. Kipreos, E.T. and J.Y.J. Wang. (1992).  Cell cycle-regulated binding of c-Abl tyrosine kinase to DNA.  Science 256:382-385.

 

46. Lin, B.T.-Y. and J.Y.J. Wang. (1992). Cell cycle regulation of retinoblastoma protein phosphorylation.  In: Regulation of the Eukaryotic Cell Cycle, Vol. 170. Ciba Foundation Symposia, pp. 227-243.

 

47. Renshaw, M.W., E.T. Kipreos, M.R. Albrecht and J.Y.J. Wang. (1992).  Oncogenic v-Abl tyrosine kinase can inhibit or stimulate growth depending on the cell context.  EMBO J. 11:3941-3951.

 

48. Wang, J.Y.J. (1992).  Modeling chronic myelogenous leukemia.  Current Biol. 2:70-72.

 

49. Wang, J.Y.J. (1992).  Oncoprotein phosphorylation and cell cycle control.  Biochim. Biophys. Acta 1114:179-192.

 

50. Wang, J.Y.J. (1993). Abl tyrosine kinase in signal transduction and cell-cycle regulation.  Current Opinion in Genetics and Development  3: 35-43.

 

51. McWhirter, J.R. and J.Y.J. Wang. (1993).  An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia-chromosome-positive human leukemias.  EMBO J. 12:1533-1546.

 

52. Wang, J.Y.J. (1993).  Tumour suppressor genes, the cell cycle and cancer.  Quart. Rev. Biol. 68:314.

 

53. Baskaran, R., M.E. Dahmus and J.Y.J. Wang. (1993).  Tyrosine phosphorylation of mammalian RNA polymerase II carboxylterminal domain.  Proc. Natl. Acad. Sci. USA 90:11167-11171.  [Accompanied by Commentary]

 

54. Welch, P.J. and J.Y.J. Wang. (1993).  A C-terminal protein binding domain in RB regulates the nuclear c-Abl tyrosine kinase in the cell cycle.  Cell 75:779-790.

 

55. McWhirter, J.R., D.L. Galasso and J.Y.J. Wang. (1993).  A coiled-coil oligomerization domain of BCR is essential for the transforming function of BCR-ABL oncoproteins.  Mol. Cell. Biol. 13:7587-7597.

 

56. Wang, J.Y.J. and J.R. McWhirter. (1994).  Protein tyrosine kinase dependent signaling pathways.  Trends Cardio. Med. 4:264-270.

 

57. Guo, J.Q., J.Y. Lian, Y.M. Xian, A.B. Deisseroth, S.A. Stass, J.Y.J. Wang and R.B. Arlinghaus. (1994).  BCR-ABL protein expression in peripheral blood cells of chronic myelogenous leukemia patients undergoing therapy.  Blood 83:3629-3637.

 

58. Wang, J.Y.J., E.S. Knudsen and P.J. Welch. (1994). The retinoblastoma tumor suppressor protein.  In: Advances in Cancer Research, Vol. 64.  Van der Wonde, G and G. Klein, eds. Academic Press, San Diego, CA. pp. 25-84.

 

59. Wang, J.Y.J. (1994).  Nuclear protein tyrosine kinases.  TIBS 19:373-376.

 

60. Duyster, J., R. Baskaran and J.Y.J. Wang. (1995).  SH2 domain as a specificity determinant in the c-Abl mediated tyrosine phosphorylation of RNA polymerase II-CTD.  Proc. Natl. Acad. Sci. USA 92: 1555-1559.

 

61. Renshaw, M.W., J.R. McWhirter and J.Y.J. Wang. (1995).  The human leukemic oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation.  Mol. Cell. Biol. 15: 1286-1293. 

 

62. Welch, P.J. and J.Y.J. Wang. (1995).  Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.  Genes Dev. 9:31-46

 

63. Huang, T.S., J. Duyster and J.Y.J. Wang. (1995).  Biological response to phorbol ester determined by alternative G1 pathways.  Proc. Natl. Acad. Sci. USA 92:4793-4797.

 

64. Welch, P.J. and J.Y.J. Wang. (1995) Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase dependent and independent mechanisms.  Mol. Cell. Biol. 15:5542-5551

 

65. Wang, J.Y.J. (1995) Review of Oncogene, 2nd Ed.  Trends Cell Biol. 6:79-80.

 

66. Renshaw, M.W., Lea-Chou, E. and J.Y.J. Wang. (1996) Rac is required for v-Abl tyrosine kinase to activate mitogenesis.  Curr. Biol. 6: 76-83

 

67. Baskaran, R., G.G. Chiang and J.Y.J. Wang. (1996).  Identification of a binding site in c-Abl tyrosine kinase for the C-terminal repeated domain of RNA polymerase II. Mol. Cell. Biol. 16: 3361-3369

 

68. Knudsen, E.S. and J.Y.J. Wang. (1996).  Differential regulation of retinoblastoma protein function by specific cdk phosphorylation sites.  J. Biol. Chem. 271:8313-8320.

 

69. Chen, Y., E.S. Knudsen, and J.Y.J. Wang. (1996).  Cells arrested in G1 by v-Abl tyrosine kinase do not express cyclin A despite the hyperphosphorylation of RB. J. Biol. Chem. 271:19637-19640.

 

70. Miao, Y.-J., and J.Y.J. Wang. (1996).  Binding of A/T-rich DNA by three HMG1-like domains in the c-Abl tyrosine kinase.  J. Biol. Chem. 271:22823-22830.

 

71. Liu, Z-G., R. Baskaran, E. Lea-Chou, L.D. Wood, M. Karin and J.Y.J. Wang. (1996).  Mouse fibroblasts exhibit three distinct signaling response to genotoxic stress.  Nature 384:273-276 [Accompanied by News and Views]

 

72. Knudsen, K.E., E.S. Knudsen, J.Y.J. Wang, and S. Subramani. (1996).  p34cdc2 activity is maintained upon activation of the replication checkpoint in S. pombe.  Proc. Natl. Acad. Sci. USA 93:8278-8283.

 

73. Lewis, L.M., R. Baskaran, S. Taagepera, M.A. Schwartz and J.Y.J. Wang. (1996).  Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport.  Proc. Natl. Acad. Sci. USA  93:15174-15179.

 

74. Chen, Y., E.S. Knudsen and J.Y.J. Wang. (1996). The RB/p107/p130 phosphorylation pathway is not inhibited in rapamycin-induced G1 prolongation of NIH3T3 cells.  Oncogene  13:1765-1771.

 

75. Arap, W., E.S. Knudsen, J.Y.J. Wang, W.K. Cavenee and H.-J.S. Huang (1997).  Point mutations can inactivate in vitro and in vivo activities of p16Ink4a/cdkn2A in human glioma. Oncogene 14:603-609.

 

76. Wang, J.Y.J. (1997).  Retinoblastoma protein in growth suppression and death protection.  Curr. Opion. Genet. Dev. 7:39-45.

 

77. Tan, X., S. J. Martin, D.R. Green and J.Y.J. Wang (1997).  Degradation of retinoblastoma protein in tumor necrosis factor and CD95-induced cell death.  J. Biol. Chem. 272:9613-9616.

 

78. Baskaran, R., L.D. Wood, Y. L.L. Whitaker, C. E. Canman, S.E. Morgan, Xu. C. Barlow, D. Baltimore, A. Wynshaw-Boris, M.B. Kastan and J.Y.J. Wang. (1997).   Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation.  Nature 387:516-519. [Accompanied by News and Views]

 

79. McWhirter, J.R., and J.Y.J. Wang. (1997). Effect of Bcr sequences on the function of Bcr-Abl oncoprotein.  Oncogene 15:1625-1634.

 

80. Nehme, A., R., Baskaran, S. Aebi, D. Fink, S. Nebel, B. Cenni, B., J.Y.J. Wang, S.B. Howell, S.B., and R.D. Christen. (1997).  Differential induction of c-Jun NH2-terminal kinase and c-Abl tyrosine kinase in DNA mismatch repair-proficient and deficient cells exposed to cisplatin.  Cancer Res. 57:3253-3258.

 

81. Baskaran, R., G.G Chiang, T. Mysliwiec, G. Krul and J.Y.J. Wang. (1997). Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by Abl-related-gene (Arg) encoded tyrosine kinase.  J. Biol. Chem. 272:18905-18909.

 

82. Knudsen, E.S. and J.Y.J. Wang. (1997). Dual mechanisms for the inhibition of E2F binding by RB phosphorylation.  Mol. Cell. Biol. 17: 5771-5783.

 

83. Arap, W., E. S. Knudsen, D. Sidransky, J.Y.J. Wang, H-J. S. Huang and W.K. Cavenee. (1997).  Functional analysis of wild type and malignant glioma-derived CDKN2b alleles: evidence for an RB-independent growth suppression pathway.  Oncogene 15:2013-2020.    

 

84. Puri, P.L., V. Sartorelli, X-J Yang, Y Hamamori, L Kedes, J.Y.J. Wang, A. Graessmann, Y. Nakatani and M. Levrero. (1997) The acetyltransferase PCAF is essential for muscle differentiation. Mol. Cell 1: 35-45.   

 

85. Obeyesekere, M.N., E.S. Knudsen, J.Y.J. Wang and O. Zimmerman. (1997). A mathematical model of the regulation of the G1 phase of Rb+/+ and Rb-/- mouse embryonic fibroblasts and an osteosarcoma cell line.  Cell Prolif. 30: 171-194.

 

86. Knudsen, E.S., and J.Y.J. Wang. (1998). Hyperphosphorylated p107 and p130 bind to T-antigen: identification of a critical regulatory sequence present in RB but not in p107/p130.  Oncogene 16: 1655-1663.

 

87. Tan, X. and J.Y.J. Wang. (1998).  The caspase--RB connection in cell death.  Trends in Cell Biol. 8: 116-120.

 

88. Wang, J.Y.J. (1998).  Cellular Responses to DNA Damage.  Curr. Opion. Cell. Biol. 10: 240-247.

 

89. Whitaker, L.L., H. Su, R. Baskaran, E.S. Knudsen and J.Y.J. Wang. (1998). Growth suppression by an E2F-binding defective retinoblastoma protein: contribution from the RB C-pocket. Mol. Cell. Biol. 18:4032-4042.

 

90. Knudsen, E.S., C. Buckmaster, T-T Chen, J.R. Feramisco and J.Y.J. Wang. (1998). Inhibition of DNA synthesis by RB: Effects on G1/S transition and S-phase progression.  Genes & Dev. 12: 2278-2292.

 

91. Taagepera, S., D. McDonald, J.E. Loeb, L.L. Whitaker, A.K. MacLeod, J.Y.J. Wang and T.J. Hope. (1998). Nuclear-cytoplasmic shuttling of c-Abl tyrosine kinase. Proc. Natl. Acad. Sci. 95:7457-7462.

 

92. Wang, J.Y.J. (1998).  Protein kinases entering the information age.  J. Biomed. Sci. 5:73.

 

93. Danial, N.N., J.A. Losman, T. Lu, N. Yip, K. Krishnan, J. Krolewski, S.P. Goff, J.Y.J. Wang and P.B. Rothman. (1998).  Direct Interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation.  Mol. Cell. Biol. 18: 6795-6804.

 

94. Bai, R.Y., T. Jahn, S. Schrem, G. Munzert, K.M. Weidner, J.Y.J. Wang, and J. Duyster (1998).  The SH2-containing adapter protein GRB10 interacts with BCR-ABL.  Oncogene 17:941-948.

 

95. Nehme, A., R. Baskaran, S. Nebel, D. Fink, S.B. Howell, J.Y.J. Wang and R.D, Christen. (1999).  Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells.  British Journal of Cancer 79:1104-1110.

 

96. Hamamori, Y., V. Sartorelli, V. Ogrysko, P.L. Puri, H-Y. Wu, J.Y.J. Wang, Y. Nakatani, and L. Kedes. (1999).  Regulation of histone acetyultransferases p300 and PCAF by twist and E1A.  Cell  96:405-413.

 

97. Baskaran, R., S.R. Escobar and J.Y.J. Wang. (1999). Nuclear c-Abl is a CTD-tyrosine kinase specific for the mammalian RNA polymerase II: possible role in transcription elongation.  Cell Growth & Differentiation 10:387-396. 

 

98. Gong, J., A. Costanzo, H-Q. Yang, G. Melino, W.G. Kaelin, M. Levero, and J.Y.J. Wang. (1999).  Tyrosine kinase c-Abl regulates p73 in apoptotic response to DNA damage by cisplatin. Nature 399: 806-809 [Accompanied by News and Views].

 

99. Sartorelli, V., P.L. Puri, Y. Hamamori, V. Ogryzko, G. Chung, Y. Nakatani, J.Y.J. Wang, and L. Kedes. (1999). Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle differentiation program.  Mol. Cell  4: 725-734.

 

100. Levrero, M., V. De Laurenzi, A. Costanzo, J. Gong, G. Melino, and J. Y. J. Wang. (1999).  Structure, function and regulation of p63 and p73.  Cell Death & Diff. 6:1146-1153.

 

101. Wang, J.Y.J. (2000).  Integrative signaling through c-Abl: a tyrosine kinase with nuclear and cytoplasmic functions.  In: Cancer Drug Discovery and Development: Signaling Networks and Cell Cycle Control.  Gutkind, J.S. ed. Humana Press, Totowa,  NJ. pp 303-327.

 

102. Wang, J. Y. J. and R. D. Kolodner (2000). Meeting report: Keystone Symposia on Molecular and Cellular Biology: ÓThe molecular basis of cancerÓ.  Biochimica et Biophysica Acta 1470: R21-R28.  

 

103. Puri, P.L., Z. Wu, P. Zhang, L.D. Wood, K. Bhakta, M. Karin, J. Han, J. Feramisco and J.Y.J. Wang. (2000). Induction of terminal differentiation by the constitutive activation of p38 MAP-kinase in human rhabdomyosarcom cells.  Genes & Dev. 14: 574-584.

 

104. Glover, R.T., M. Angiolieri, S. Kelly, D.T. Monaghan, J.Y.J. Wang, T.E. Smithgall and A.L. Buller (2000).  Interaction of the NMDA receptor NR2 subunit with the c-Abl tyrosine kinase.  J. Biol. Chem. 275: 12725-12729.

 

105. Levrero, M., V. DeLaurenzi, A. Costanzo, J. Gong, J.Y.J. Wang, and G. Melino (2000).  The p53/p63/p73 family: biological redundancy or distinct functions?  J. Cell. Sci. 113: 1661-1670.   

 

106. Wang, J. Y. J. (2000).  New link in a web of human genes.  Nature 405: 404-405.

 

107. Wu, Z., P.J. Woodring, K. Bhakta, K. Tamura, F. Wen, J. R. Feramisco, M. Karin, J.Y.J. Wang, and P. L. Puri. (2000). p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps.  Mol. Cell. Biol. 20: 3951-3964.

 

108. Chen, T-T., and J. Y. J. Wang. (2000). Establishment of irreversible growth arrest in myogenic differentiation requires the RB LxCxE-binding function.  Mol. Cell. Biol. 20: 5571-5580.

 

109. Knudsen, K.E., D. Booth, S. Naderi, Z. Sever-Chroneos , A. F. Fribourg, I. C. Hunton, J. R. Feramisco, J. Y.J. Wang and E.S. Knudsen. (2000).  RB-dependent S-phase response to DNA damage.  Mol. Cell. Biol.  20: 7751-7763.

 

110. Wang, J.Y.J. (2000). Regulation of cell death by the Abl tyrosine kinase.  Oncogene 19: 5643-5650.

 

111. Wood, L.D., T.L. Halvorsen, S. Dhar, J.A. Baur, R.K. Pandita, W. Wright, M.P. Hande, G. Calaf, F. Levine, J.W. Shay, J.Y.J. Wang, and T.K. Pandita. (2001). Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression.  Oncogene 20: 278-288.

 

112. Vigneri, P. and J. Y. J. Wang. (2001). Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.  Nature Med. 7: 228-234.

 

113. Pennaneach V., I. Salles-Passador, A. Munshi, K. Regazzoni, H. Brickner, F. Dick, N. Dyson, T-T. Chen, J.Y.J. Wang, R. Fotedar, and A. Fotedar. (2001).  The large subunit of replication factor c promotes cell survival after UV induced DNA damage in an LXCXE motif- and RB-dependent manner.  Mol. Cell 7: 715-727.

 

114. Wang, J.Y.J., S. Naderi and T-T. Chen. (2001).  Role of retinoblastoma tumor suppressor protein in DNA damage response.  Acta. Oncologica  40: 689-695.

 

115. Woodring, P.J., T. Hunter and J.Y.J. Wang (2001).  Inhibition of c-Abl tyrosine kinase activity by filamentous actin.  J. Biol. Chem. 276: 27104-27110.

 

116. Frasca, F., P. Vigneri, V. Vella, R. Vigneri and J.Y.J. Wang (2001).  Tyrosine kinase inhibitor STI571 enhances the motile response of thyroid cancer cells to hepatocyte growth factor.  Oncogene  20: 3845-3856.

 

117. Sun, J., M.A. Schwartz,  J.Y.J. Wang, T. Wiedmer and P.J. Sims (2001).  C-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1.  J. Biol. Chem. 276: 28984-28990.

 

118. Wang, J. Y. J. and S.W. Ki (2001).  Choosing between growth arrest and apoptosis through RB, c-Abl and p73.  Biochem. Soc. Trans. 29: 666-673.

 

119. Puri, P.L., S. Iezzi, P. Stiegler, T-T Chen, R. L. Schiltz, G. E.O. Muscat, A. Giordano, L. Kedes, J.Y.J.Wang, and V. Sartorelli (2001).  Class I histone deacetylases

sequentially interact with MyoD and pRb during skeletal myogenesis.  Mol. Cell  8: 885-897.

 

120. Wang, J.Y.J. (2001).  DNA damage and apoptosis.  Cell Death & Diff. 8: 1047-1048.

 

121. Woodring, P.J., E. D. Litwack,   D. D. OÕLeary, G. R. Lucero,  J.Y.J. Wang, and T. Hunter (2002).  Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension.  J. Cell Biol.  156:879-892.

 

122. Catani, M.V., A.Costanzo, I. Savini, M. Levrero , V. De Laurenzi,  J.Y.J. Wang, G. Melino, and L. Avigliano (2002). Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage. Biochemical  Journal 364: 441-447.

 

123. Wang, J. Y. J. and S.W. Ki (2002).  Cellular responses to DNA damage.  In: Encyclopedia of Cancer, Second Edition, Vol. 1.  Bertino, J. ed. Academic Press, San Diego, CA. pp 425-432.

 

124.  Naderi, S., I.C. Hunton, and J.Y.J. Wang (2002). Radiation dose-dependent maintenance of G2 arrest requires retinoblastoma protein. Cell Cycle 1:193-200.

 

125. Chau, B.N., H. Borges, T-T Chen, A. Masselli, I.C. Hunton, and J. Y. J. Wang (2002). Signal dependent protection from apoptosis in mice with caspase-resistant RB.  Nature Cell Biol. 4: 757-765.

 

126. Puri, P.L., K. Bhakta, L. D. Wood, A. Costanzo, J. Zhu, and J. Y. J. Wang (2002).  A myogenic differentiation checkpoint activated by genotoxic stress.  Nature Genet. 32:585-593.

 

127. Shimodaira, H., A. Yoshioka-Yamashita,  R. Kolodner and J.Y.J. Wang (2003). Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc. Natl. Acad. Sci. USA 100:2420-2425.

 

128. Chau, B.N. and J.Y.J. Wang (2003). Coordinated regulation of life and death by RB. Nature Rev. Cancer 3:130-138.

 

129.  Woodring, P.J., T. Hunter, J.Y.J. Wang (2003). Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases. J. Cell Sci. 116:2613-2626.

 

130.  Vella, V. J. Zhu, F. Frasca, C-Y Li, P. Vigneri, R. Vigneri, J.Y.J. Wang (2003). Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function. J. Biol. Chem. 278:25151-25157.

 

131.  Guerra, B., O-G Issinger, J.Y.J. Wang (2003). Modulation of human checkpoint kinase Chk1 by the regulatory b-subunit of protein kinase CK2. Oncogene 22:4933-4942.

 

132. Yee, A.S. and J.Y.J. Wang (2003). Role of RB/E2F in G1 phase progression. In: G1 Phase Progression, pp 77-92. Boonstra, J. ed. Landes Bioscience, Georgetown, TX. 

 

133. Wang, J.Y.J. (2003). Abl in cell signaling. In: Handbook of Cell Signaling. Part III. Nuclear Responses, Chapter 307, pp. 249-256. Bradshaw, R. and E. Dennis, eds. Academic Press, San Diego, CA.

 

134. Truong, T., G. Sun, M. Doorly, J.Y.J. Wang, and M.A. Schwartz (2003). Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl. Proc. Natl. Acad. Sci.  USA 100:10281-10286.

 

135.  Wang, J.Y.J. (2004) Controlling Abl: auto-inhibition and co-inhibition? Nature Cell Biology.  6: 3-7.

 

136.   Zhu, J. and J.Y.J. Wang (2004). Death by Abl, a matter of location. In: Current Topics in Developmental Biology, Schatten, G. ed., Academic Press, San Diego, CA. In Press.

 

137.  Borges, H.L., C. Chao, Y. Xu, R. Linden, J.Y.J. Wang (2004). Radiation dose-dependent requirement for ATM phosphorylation of p53 in apoptosis of neonatal retina. Cell Death and Diff. In Press.

 

138.   Wang, J.Y.J. (2004) ÒCell Cycle: DNA Damage CheckpointsÓ in Encclopedia of Biological Chemistry, ed. Don Cleveland. Elsevier/Academic Press. In Press.

 

139.  Chau, B. N., Wan, Y.Y., DeGregori, J. and Wang, J. Y.J. (2004) TNF-a-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation. Mol. Cell Biol.  Submitted.

 

140.  Woodring, P.J., J. Meisenhelder, S.A. Johnson, G. Zhou, J. Field, K. Shah, F. Bladt, T. Pawson, M. Niki, P.P. Pandolfi, J.Y.J. Wang, and T. Hunter (2004). Phosphorylation of Dok1 by c-Abl tyrosine kinase increases filopodia during cell spreading.   J. Cell Biol. Submitted.