Research / Clinical
Summary
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William Trogler, PhD
Professor, Chemistry & Biochemistry
Hematologic Malignancies Program
Contact by Email
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Diseases/Research Topics
Antibody Arrays, Array, Fabrication, Nanomaterials, Sensors
William Trogler's research in the Moores Cancer Center focuses on new nanostructured materials for gene and drug delivery, as well as surface functional reagents for cell patterning. New aqueous and air stable reagents have been prepared for attaching cell specific antibodies or proteins on elemental oxide surfaces. Methods for attaching nonbiofouling surface reagents have also been developed. These studies are being done in collaboration with Drs. Blair and Kummel’s research groups for new analytical approaches to cancer cell detection.
A second effort has been the synthesis of monodisperse porous hollow shell nanoparticles in the 40 to 500 nm size range. Applications in drug delivery for cancer are being conducted in collaboration with Dr. Carson’s research group, imaging applications are being explored in collaboration with Drs. Esener and Mattrey’s groups, and gene transfer is being explored with Drs. Kipps and Messmer.
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