Research / Clinical
Summary
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Diseases/Research Topics
Angiogenesis, Breast Cancer, Cancer, Colon Cancer, Contrast Media, MRI, Sentinel Lymph Nodes, Targeted Diagnostic Agents, Tomography, Ultrasound, Urologic Cancer, Virtual Colonoscopy, X-ray Computed Tomography
Dr. Mattrey's cancer-related research program consists of the following projects:
Ultrasound Contrast Media Program
- Development and testing of contrast specific imaging techniques
- Vascular imaging for the detection of wall abnormalities
- Solid organ imaging for lesion detection and characterization
- Several clinical studies under a Physician Sponsored IND
- Effect of systemic and focal therapy on tumor vascularity and
viability
Blood Pool Contrast Media Applications in CT, MRI, and Optical Imaging
Molecular and Cellular Imaging
- Targeted ultrasound contrast media
- Testing of MR probes directed to cellular and molecular targets
- Signal augmentation techniques
Breast Cancer
Detection and characterization of sentinel lymph nodes with microbubble
Assessment of Angiogenesis Using Optical Agents and Near-IR Spectroscopy
Virtual Colonoscopy for Cancer Screening
- Techniques to recognize adherent stools from polyps
- Computer aided detection of polyps
- Comparison of EBCT virtual colonoscopy to colonscopy
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