Histology and Immunohistochemistry

Co-Director

Nissi M. Varki, MD
Professor of Pathology 
Phone: 858-534-4933
Email: nvarki@ucsd.edu

Contact

Laarni Gapuz, MT (ASCP)
Phone: 858-822-1011
Email: lgapuz@ucsd.edu
Location: Moores Cancer Center, 3855 Health Sciences Drive #0815, #5314 (fifth floor)

Alternate:

MaryAnn Lawrence, HT (ASCP)
Histology Lab Manager
Phone: 858-822-1011
Email mlawrence@ucsd.edu
Location: Moores Cancer Center Histology Core, fifth floor

Service profile

  • Freezing and embedding of tissues for histology
  • Frozen sections
  • Paraffin blocks processing and Paraffin sections
  • Hematoxylin and Eosin staining of sections
  • Specialized histochemical staining
  • Individualized immunohistochemical assays
  • Specialized assays: TUNEL, BrdU, beta galactosidase, etc.
  • Interpretation assistance; mouse histology and pathology
  • Design and interpretation of immunohistology and in situ hybridization analysis

Overview

This facility allows a complete histologic phenotypic analysis of tissues from genetically altered mice; embryo to adult. It is indispensable for providing quality control for the presence of cancer in a human tissue sample prior to use in biochemical or molecular biological analysis. Conversely, it establishes the absence of tumor in tissue utilized as a normal control for similar experiments.

Important information

Graphic example of how genetically altered animals can be analyzed optimally

(Click image for full size)

Graphic example of how genetically altered animals can be analyzed optimally