Histology and Immunohistochemistry

Phone: 858-822-1011
Email: ucsdhistologycore@gmail.com
Location: Moores Cancer Center, 3855 Health Sciences Drive, #5314 (fifth-floor lab)
Mail Code: MC 0815

Co-Director

Nissi M. Varki, MD
Professor of Pathology 
Phone: 858-534-4933
Email: nvarki@ucsd.edu
Location: BRF2 Osler Lane 4122, 8500 Gilman Drive, MC 0687
Online bio

Moores Cancer Center Histology Core Contacts

Histotechnologists:

Service profile

  • Freezing and embedding of tissues for histology
  • Frozen sections
  • Paraffin blocks processing and Paraffin sections
  • Hematoxylin and Eosin staining of sections
  • Specialized histochemical staining
  • Individualized immunohistochemical assays
  • Specialized assays: TUNEL, BrdU, beta galactosidase, etc.
  • Interpretation assistance; mouse histology and pathology
  • Design and interpretation of immunohistology and in situ hybridization analysis

Overview

This facility allows a complete histologic phenotypic analysis of tissues from genetically altered mice; embryo to adult. It is indispensable for providing quality control for the presence of cancer in a human tissue sample prior to use in biochemical or molecular biological analysis. Conversely, it establishes the absence of tumor in tissue utilized as a normal control for similar experiments.

Important information

Graphic example of how genetically altered animals can be analyzed optimally

(Click image for full size)

Graphic example of how genetically altered animals can be analyzed optimally