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Finding and Surviving Ovarian Cancer Side Effects Are there side effects from the radiation? The radiation will still kill some healthy cells in that area of the body. Radiation causes some various things to happen. It may cause skin changes such as redness or peeling, vaginal or rectal pain, vaginal narrowing, nausea, loss of appetite, tiredness, feeling the need to urinate more often, diarrhea, and/or softening of your bones. Most of these side effects last only about two weeks after you stop radiation. However, there are long-term side effects. Some women report sexual difficulties and early menopause. You should talk with your doctor if these side effects occur or if the short term side effects last longer than they should.
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