Research / Clinical
Summary
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Mark Fuster, MD
Assistant Professor, Medicine
Tumor Growth, Invasion & Metastasis Program
Contact by Email
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Diseases/Research Topics
Angiogenesis, Cancer, Endothelium, Lung Cancer, Lymphatic, Metastasis, Proteoglycans
As a Pulmonary and Critical Care specialist at UCSD in the Department of Medicine, Dr. Fuster's research centers on the vascular biology of tumor progression, with a special clinical interest in lung cancer. While caring for lung cancer patients during his clinical practice at the VA and UCSD, his long-term goals include translating insights on the biology of tumor progression toward the care of lung cancer patients.
Dr. Fuster's laboratory studies the glycobiology of tumor vascularization and examines mechanisms that control angiogenesis, lymphangiogenesis, tumor-vascular invasion, and both hematogenous and lymphatic metastasis.
Some of his recent publications delineate critical roles played by both selectin ligands on tumor cells as well as heparan sulfate proteoglycans on endothelium in mediating the pathophysiology of hematogenous metastasis and tumor angiogenesis.
Together with Cancer Center collaborators, he is currently expanding his studies to discover critical roles played by tumor- and endothelial glycans in controlling major vascular events that mediate metastasis.
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