Cancer Center Programs

Members of the Cancer Center at UCSD have developed strong, thriving, well-funded programs of research.

Biology
This program is focused on fundamental mechanisms in two general areas of biology: signal transduction and developmental biology. Acknowledging the complexity of the signal transduction network that governs the basic processes of cell proliferation, differentiation and cell death, members of Cancer Biology also develop tools for high-throughput and computational analyses of the regulatory network.

Genetics
Investigators in this program focus on classical and molecular genetics and systems biology approaches in the study of cancer, both for understanding the genetic basis of the disease and to identify targets for therapeutic intervention. With the increasing availability of genome sequences and powerful new genetic technologies, the time may never be better to obtain genetic insights into the development of cancer.

Prevention & Control
This program is focused on improving the current knowledge base to promote overall reductions in cancer incidence, mortality and morbidity as outlined by the 2010 Health Goals for the nation. Studies include: (1) promoting the decline in tobacco consumption in the United States; (2) improving lifestyle patterns observed to be protective against cancer; (3) studying the efficacy of cancer prevention efforts; and (4) improving exposure measures used in cancer prevention and control studies.

Symptom Control
Recognizing and treating emerging psychiatric disorders such as depression in cancer patients and their spouses; improving the diagnosis of the etiology of cancer pain syndromes; developing more efficacious pharmacologies and regimens for pain relief; relieving fatigue and improving quality of life in cancer patients; combating the physiologic effects of stress on cancer patients and their families.

Hematologic Malignancies
Investigators seek to improve our understanding of molecular characteristics and treatment of leukemias and lymphomas. Examining the differences between cancer and normal cells has provided insight into the molecular and biochemical features that define the malignant phenotype. Ultimate understanding of these mechanisms will help investigators to identify molecular pathways or antigens that are receptive to drugs and/or immune therapy.

Reducing Cancer Disparities
The predominant focus of members in this program is to apply the same mechanisms applied in white/Anglo populations to be tested in diverse and vulnerable populations.  Emphasis is placed on racially and ethnically diverse communities, at-risk youth, and the handicapped in order to develop a synergy through their interaction. 

Tumor Growth, Invasion and Metastasis
The primary interest of members in this program is to develop novel therapeutics and diagnostic tools based on insights into the basic mechanisms that control the growth and drug sensitivity of tumors, how they interact and invade into adjacent tissues, and how they metastasize to distant sites. 

SDSU / UCSD Cancer Partnership Planning