Research / Clinical
Summary
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Diseases/Research Topics
Auto-digestion as Inflammatory Mechanism, Inflammation, Inflammatory Processes that Lead to Malignant Transformation In Vivo, Microcirculation, Mechanotransduction
Specifically we explore trigger mechanisms for inflammation due to:
- auto-digestion by pancreatic digestive enzymes in-vivo activators and cytotoxic mediators
- molecular mechanisms for cell and organ dysfunction involving proteolytic enzymes
- blockade of digestive enzymes as mechanism to attenuate inflammation and organ injury
- mechanisms that control mechanotransduction by fluid shear stress in circulating leukocytes
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