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Research / Clinical Summary

Gail Laughlin, PhD
Assistant Professor, Family & Preventive Medicine
Cancer Prevention & Control Program
Contact by Email

Diseases/Research Topics
Biomarkers, Breast Cancer, Cancer, Cardiovascular Disease, Cognitive Function, Epidemiology, Mammographic Density, Metabolic Hormones, Sex Hormones

Dr. Laughlin's research interest is focused on the role of endogenous hormones in the development of diseases of aging, including breast cancer, prostate cancer, cancer mortality, mammographic breast density, cardiovascular disease, cognitive function, diabetes and osteoporosis. She has an extensive background in endocrinology based on more than 20 years of research in the Reproductive Endocrinology division of SSC Yen at UCSD.

Dr. Laughlin’s investigations have encompassed hypothalamic, pituitary, adrenal and gonadal hormones, as well as a number of metabolic hormones (the GH-IGF axis, adiponectin, leptin, insulin, glucose) and melatonin.

In addition, Dr. Laughlin is a WHEL (Women's Healthy Eating and Living) Study investigator and a primary member of the Rancho Bernardo Study of healthy aging. She was a participant in the Endogenous Hormones and Breast Cancer Collaborative Group meetings at Oxford and several subsequent publications, and is active in studies at UCLA of the biological determinants of mammographic density using hormone data from the PEPI (Postmenopausal Estrogen/Progestin Interventions) study.

Dr. Laughlin is particularly interested in the role of endogenous sex hormones in determining sex differences in diseases of aging, and in defining the biological factors linking diseases of the heart and those of the bone, brain, and breast.

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