Transgenic Mouse

Director

Pamela Mellon, PhD
Professor of Reproductive Medicine and Neuroscience
Phone: 858-534-1140
E-mail: mellonadmin@ucsd.edu

Contact

For Pronuclear Microinjection inquiries, email Jun Zhao, juzhao@ucsd.edu

For Embryo Rederivation, Embryo Cryopreservation, In-Vitro Fertilization inquiries, email Jun Zhao, juzhao@ucsd.edu

For Sperm Cryopreservation inquiries, email Jun Zhao, juzhao@ucsd.edu

For Embryonic Stem Cell inquiries, email Ella Kothari, ekothari@ucsd.edu

For Blastocyst Injection inquiries, email Ella Kothari, ekothari@ucsd.edu

Service profile

Overview

The Transgenic Mouse shared resource is a state-of-the-art facility that has an outstanding track record in the production of genetically altered mice. Transgenic mice carrying new or novel genes are created by microinjection of DNA into the pronuclei of fertilized eggs. Knock-out mice lacking specific genes of interest are created by homologous recombination in embryonic stem cells followed by injection into blastocysts to create chimeric mice. Highly experienced personnel produce transgenic and knock-out mice for UC San Diego investigators at very reasonable cost and with very short lead times.

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