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Archive Document ID:
64
2/7/2001 CC Browser
Schottenfeld to Speak
David Shottenfeld, M.D., Professor of Epidemiology and Internal Medicine at the University of Michigan Schools of Medicine and Public Health, is scheduled to speak tomorrow, February 8, at 12:00 pm at the Center for Molecular Genetics Large Conference Room. His lecture is entitled “Molecular Epidemiology of Pre-Cancerous Lesions of the Gastrointestinal Tract,” and interested parties can contact Melinda Richards at mrichards@ccis2.ucsd.edu or Ext. 47255 for further information. (Return to Top)
News from the Digital Imaging Front
The Cancer Center's Digital Imaging and Cell Microinjection Shared Resource welcomes Stephen McMullen, Staff Research Associate. Stephen is a recent graduate of UCLA, and is available to assist or train you on DeltaVision deconvolution microscopy, image analysis and photo-output Steve can be reached at Ext. 24187 or swmcmullen@ucsd.edu. Carolan Buckmaster, Staff Research Associate, continues to provide excellent service training for microinjection or immunofluorescence microscopy, and can be contacted at Ext. 48803 or cbuckmaster@ucsd.edu.  | | This image was captured by William Biggs, Ph.D. of the Webster Cavenee, Ph.D. laboratory (Ludwig Institute) using the DeltaVision microscope. The 3-D perspective view was made by Dave Nadeau at SDSCC using NPACI Scalable Visualization Tools. The image shows the localization of a growth factor receptor and its ligand on the surface of a human cell. |
The Cancer Center has provided funding to upgrade the Zeiss imaging system to real-time capability for fluorescence, phase/contrast and brightfield digital image capture with the purchase of a video capture card. According to the Resource Leader, James Feramisco, Ph.D., “We have enjoyed seeing the work of several users of this facility featured on the covers of recent journals in which their work was published.” Some of these include:Burger JA, Tsukada N, Burger M, Zvaifler NJ, Dell'Aquila M, Kipps TJ: Blood-derived "nurse-like" cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis via stromal-cell-derived factor-1. Blood 96:2655-2663, 2000Adams JW, Pagel AL, Means CK, Oksenberg D, Armstrong RC, and Brown JH: Cardiomyocyte Apoptosis Induced by Gq Signaling Is Mediated by Permeability Transition Pore Formation and Activation of the Mitochondrial Death Pathway. Circ. Res. 87:1180-1187, 2000Scully KM, Jacobson EM, Jepsen K, Lunyak V, Viadiu H, Carrière C, Rose DW, Hooshmand F, Aggarwal AK, Rosenfeld MG: Allosteric Effects of Pit-1 DNA Sites on Long-Term Repression in Cell Type Specification. Science 290:1127-1131, 2000 According to Dr. Faramisco, “The Kipps lab used the Hamamatsu camera and the attached Zeiss microscope, while the Brown and Rosenfeld labs used the DeltaVision deconvolution imaging system. For the Brown and Rosenfeld covers, 3-Dimensional perspective views were rendered by our colleagues Dave Nadeau, Alex DeCastro and Jon Genetti at the VisLab at SDSCC using NPACI Scalable Visualization Tools.” (Return to Top)
 Member Publications
Borsig L, Wong R, Feramisco J, Nadeau DR, Varki NM, Varki A: Heparin and Cancer Revisited: Novel Mechanistic Connections Involving Platelets, P-Selectin, Carcinoma Mucins and Tumor Metastasis. Proc. Natl. Acad. Sci. USA, 2001 in press.Bouvet M, Nardin SR, Burton DW, Behling C, Carethers JM, Moossa AR, Deftos LJ: Human Pancreatic Adenocarcinomas Express Parathyroid Hormone-related Protein. J. of Clinical Endocrinology and Metabolism 86(1):310-316, 2001. Hovell MF, Zakarian JM, Wahlgren R, Matt GE: Reducing Children’s Exposure to Environmental Tobacco Smoke: The Empirical Evidence and Directions for Future Research. Tobacco Control 9:(Suppl II):ii40-ii47, 2000. Lin X, Ramamurthi K, Mishima M, Kondo A, Howell SB: p53 Interacts with the DNA Mismatch Repair System to Modulate the Cytotoxicity and Mutagenicity of Hydrogen Peroxide. Mol. Pharmacol. 58:1222-1229, 2000. Ricciardiello L, Laghi L, Ramamirtham P, Chang CL, Chang DK, Randolph AE, Boland CR. JC virus DNA Sequences are Frequently Present in the Human Upper and Lower Gastrointestinal Tract. Gastroenterology 119:1228-1235, 2000. published in the fall, and shows that most people carry JC virus, which we think plays a role in tumorigenesis, in their gastrointestinal tracts. Rock CL, Thomson C, Caan BJ, Flatt SW, Newman V, Ritenbaugh C, Marshall JR, Hollenbach KA, Stefanick ML, Pierce JP: Reduction in Fat Intake is Not Associated With Weight Loss in Most Women After Breast Cancer Diagnosis. Evidence from a Randomized Controlled Trial. Cancer 91:25-34, 2001. Schneiderman LJ, Gilmer T, Teetzel H: Impact of Ethics Consultations in the Intensive Care Setting: A Randomized, Controlled Trial. Critical Care Medicine 28(12):3920-3924, 2000. If you would like to share your new published or in press work with Cancer Center colleagues in a future CC Browser edition, please forward the pertinent information to dedavis@ucsd.edu. (Return to Top)
 A Guide for Your Personal Floating Holiday in 2001
- The Personal Floating Holiday is taken at the discretion of the employee, with supervisory approval.
- The holiday must be taken in a single absence prior to the end of 2001.
- It is the employee’s responsibility to request time off in advance and in consideration of the department’s staffing and operational requirements.
- An eligible employee must have received a UCSD appointment prior to or on January 3, 2001.
- An eligible employee was on pay status at least half of the working hours of the month preceding the month in which personal holiday is requested.
- The supervisor is responsible for reviewing, approving time off in accordance with the department’s operational demands.
- To record this holiday, complete an Absence Slip (UCSD Form #FO 2104), available through the Storehouse or the Cancer Center. Write “Personal Floating Holiday” under “Reason for Absence,” submit to your supervisor for approval, and forward to the Cancer Center Human Relations Department, MC0658. (Return to Top)
January Grants Exceed $3 Million
Investigator/
Cancer Center
Research Program
| Agency | Type | Period | Annual
Direct
Costs | BURNS, David
Cancer Prevention | UC Tobacco | Cont | 07/01/01-06/30/01 | $ 100,000 | CARSON, Dennis
Translational Onc | Cap CURE | New | 01/01/01-12/31/01 | 100,000 | FIRESTEIN, Gary
Translational Onc | NIH | Cont | 12/01/00-11/30/01 | 180,109 | GANIATS, Theodore
Cancer Symptom Control | NIH/Geo Washington
NIH/Geo Washington
CA HealthCare Fdn/UCLA
| Supple Cont
Cont | 07/01/99-06/30/00
07/01/00-06/30/01
02/01/01-01/31/02 | 15,314
15,357
6,264 | GLASS, Christopher
Cancer Biology | NIH | Cont | 01/15/01
12/31/01 | 193,261 | HOWELL, Stephen
Cancer Pharmacology | Clayton Fdn
Sanofi Winthrop Pharma | Cont
Cont | 01/01/01-12/31/01
07/01/00-11/30/01 | 439,602
39,816 | KUNG, Faith
Translational Onc | NIH | Cont | 01/01/01-12/31/01 | 27,316 | PATTERSON, Thomas
Cancer Symptom Control | World AIDS Fdn | New | 09/01/00-08/31/01 | 90,000 | PIERCE, John
Cancer Prevention | NIH
NIH | Cont
Supple | 12/01/00-11/30/01
12/01/01-11/30/01 | 1,997,305
111,394 | ROSENFELD, Michael
Cancer Genetics | Cap CURE | New | 01/01/01-12/31/01 | 100,000 | VARKI, Ajit
Cancer Biology | NIH | Cont | 01/0/01-12/31/01 | 247,173 | ZANETTI, Maurizio
Translational Onc | Cap CURE | New | 01/01/01-12/31/01 | 100,000 | | TOTAL AWARDS (January, 2001) | $3,762,911 |
(Return to Top)
We invite your submission of any information you think would be of interest to other members of the Cancer Center community. This might include event announcements, new employees, honors and awards, new services, new publications, shared or new equipment that is available at your location, helpful laboratory or administrative tips/techniques, etc.
For further information about any of these items, to submit new items or to provide feedback about this news communications tool, contact Deborah Davis, 822-1240, or dedavis@ucsd.edu. Please state the best way to reach you, by telephone or email if we need to clarify a submitted item.
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